This exhibition aims to bring to the public innovations made by Polish and international innovators. It will present the work of individuals, teams in companies, academics and other structures of society. It will also highlight innovations made by young people in the educational system. In this way, the public will be able to gain knowledge about these innovations and how to make them a reality.
\nScientists from the University of Warsaw have come up with a new method for mRNA stabilisation. Their invention involves replacing the seven-methylguanosine structure of mRNA with an artificial five-prime cap. This new method has many potential applications, including the development of new cancer therapies.
\nUsing this method, scientists can increase the amount of protein that can be produced by dendritic cells. These cells are vital for the development of cancer vaccines and therapies. The researchers at the University of Warsaw describe their method in a scientific journal called Nucleic Acids Research. Reviewers have hailed the article as a groundbreaking achievement in the field.
\nThe scientists at the University of Warsaw modified the “cap 5′” region of mRNA, which is a marker that enzymes attach to. Normally, mRNA only stays active for a short period of time, and enzymes within the cell destroy it in minutes. This modification makes mRNA more stable and increases protein production. It could also be used as a vaccine to prevent the growth of tumors.
\nThe method was developed in collaboration with a group of American and German scientists. They patented the method in Poland and the United States in late November 2016. While the University of Warsaw was credited with the invention, it was the US-based Louisiana State University that stepped in to help the researchers patent the technology. The two institutions agreed to share the ownership of the patents. The two groups submitted two patents, each slightly different from the other.
\nThis method has become an industry standard for producing vaccines using mRNA. It is used by biotechnology companies such as BioNTech and Pfizer. It is also used by the pharmaceutical industry to create new drugs. Yet, the role of Polish scientists in this process is not often acknowledged in mainstream media. The researchers at the University of Warsaw have been instrumental in making these new products available for the public.
\nA new patent has been issued to a group of people in Washington State, United States. The invention, called “Appature,” involves piercing a substrate. Inventors at Invention Science Fund I, Bellevue, Washington, developed the patent. There are seven co-inventors listed on the patent. They include Edward S. Boyden, Cambridge, Massachusetts; Daniel B. Cook; and Lowell L. Wood, Jr.
\nPatents awarded to Hartford Fire Insurance, Hartford, Connecticut, and Fort Lauderdale, Florida-based Citrix Systems relate to systems and methods for processing data that are used in the process of providing property and casualty insurance quotes. The systems and methods include a user interface and include data about the location of a new item. The patents also cover a process for computing the total current value of an insurance inventory.
\n\n https://www.ycombinator.com/documents/
\n https://techcrunch.com/
\n https://www.uspto.gov/learning-and-resources/startup-resources
\n https://www.sba.gov/business-guide/plan-your-business/fund-your-business
\n https://hbr.org/1998/11/how-venture-capital-works
\n http://patentpc.com/
\n http://uspto.gov/
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Inventors and Patents From the City of Charleston
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